Full Publication List at Pubmed here
2021


Pinkard H, Stuurman N, Ivanov IE, Anthony NM, Ouyang W, Li, B, Yang B, Tsuchida MA, Chhun B, Zhang G,  Mei R, Anderson M, Shepherd DP, Hunt-Isaak I, Dunn RL, Jahr W, Kato S, Royer LA, Thiagarajah JR, Eliceiri KW, Lundberg E, Mehta SB, Waller L. Pycro-Manager:open-source software for customized and reproducible microscope control. Nat Methods 2021 Mar; 18:226-228. PMID: 33674797  

Zhang YJ, Jimenez L, Azova S, Kremen J, Chan Y-M, Elhusseiny AM, Saeed H, Goldsmith J, Al-Ibraheemi A, Connell AEO, Kovbasnjuk O, Rodan L, Agrawal PB, Thiagarajah JR. Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis. Eur J Hum Genet EJHG. 2021 Feb 1; PMID: 33526876

2020

Chang D, Whiteley AT, Bugda Gwilt K, Lencer WI, Mekalanos JJ, Thiagarajah JR. Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27502–27508. PMID: 33087577

Khoshnevisan R, Anderson M, Babcock S, Anderson S, Illig D, Marquardt B, Sherkat R, Schröder K, Moll F, Hollizeck S, Rohlfs M, Walz C, Adibi P, Rezaei A, Andalib A, Koletzko S, Muise AM, Snapper SB, Klein C, Thiagarajah JR, Kotlarz D. NOX1 Regulates Collective and Planktonic Cell Migration: Insights From Patients With Pediatric-Onset IBD and NOX1 Deficiency. Inflamm Bowel Dis. 2020 Jul 17;26(8):1166–1176. PMCID: PMC7365810

Grey MJ, Cloots E, Simpson MS, LeDuc N, Serebrenik YV, De Luca H, De Sutter D, Luong P, Thiagarajah JR, Paton AW, Paton JC, Seeliger MA, Eyckerman S, Janssens S, Lencer WI. IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress. J Cell Biol. 2020 Feb 3;219(2). PMCID: PMC7041686

Luong P, Li Q, Chen P-F, Wrighton PJ, Chang D, Dwyer S, Bayer M-T, Snapper SB, Hansen SH, Thiagarajah JR, Goessling W, Lencer WI. A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization. Mol Biol Cell. 2020 19;31(7):511–519. PMCID: PMC7202069

Jardine S, Anderson S, Babcock S, Leung G, Pan J, Dhingani N, Warner N, Guo C, Siddiqui I, Kotlarz D, Dowling JJ, Melnyk RA, Snapper SB, Klein C, Thiagarajah JR, Muise AM. Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Disease Caused by TTC7A Deficiency. Gastroenterology. 2020 Mar;158(4):1000–1015. PMCID: PMC7062591

2019

Duan T, Cil O, Thiagarajah JR, Verkman AS. Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea. JCI Insight. 2019 Feb 21;4(4). PMCID: PMC6478423

2018

Luong P, Hedl M, Yan J, Zuo T, Fu T-M, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. eLife. 2018 Oct 25;7. PMCID: PMC6226287

Anez-Bustillos L, Dao DT, Potemkin AK, Perez-Atayde AR, Raphael BP, Carey AN, Kamin DS, Thiagarajah JR, Crowley M, Gura KM, Puder M. An Intravenous Fish Oil-Based Lipid Emulsion Successfully Treats Intractable Pruritus and Cholestasis in a Patient with Microvillous Inclusion Disease. Hepatol Baltim Md. 2019 Mar;69(3):1353–1356. PMCID: PMC6507398

O’Connell AE, Zhou F, Shah MS, Murphy Q, Rickner H, Kelsen J, Boyle J, Doyle JJ, Gangwani B, Thiagarajah JR, Kamin DS, Goldsmith JD, Richmond C, Breault DT, Agrawal PB. Neonatal-Onset Chronic Diarrhea Caused by Homozygous Nonsense WNT2B Mutations. Am J Hum Genet. 2018 Jun 4; PMID: 29909964

Thiagarajah JR, Kamin DS, Acra S, Goldsmith JD, Roland JT, Lencer WI, Muise AM, Goldenring JR, Avitzur Y, Martín MG, PediCODE Consortium. Advances in Evaluation of Chronic Diarrhea in Infants. Gastroenterology. 2018 Jun;154(8):2045-2059. e6. PMCID: PMC6044208

2017

Thiagarajah JR, Chang J, Goettel JA, Verkman AS, Lencer WI. Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia. Proc Natl Acad Sci U S A. 2017 17;114(3):568–573. PMCID: PMC5255594 

 Frank SR, Köllmann CP, van Lidth de Jeude JF, Thiagarajah JR, Engelholm LH, Frödin M, Hansen SH. The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. Oncogene. 2017 Mar 30;36(13):1816–1828. PMCID: PMC5366285